Research tells us that a low level of the 2-hydroxyestrone and a high level of 16 alpha-hydroxyestrone is associated with an enhanced risk of breast cancer. DIM increases 2-hydroxyestrone and therefore improves the 2/16 hydroxyestrone ratio, making it very protective for women and men at high risk for this condition.
Research by Bradlow has shown that DIM also reduces availability of 4-androstenedione for aromatization to estrone, a more dangerous form of estrogen. He concludes that DIM is more potent than I3C at protecting against breast cancer due to decreased formation of 16 alpha-hydroxyestrone from estrone. DIM supplementation improves the estrogen ratio in a favorable direction that protects both men and women without the negative effect of raising 4 hydroxyestrogen as seen with I3C. DIM does not block ovulation the way I3C does, and can be used safely along with Tamoxifen, unlike I3C. DIM should be considered first line therapy for hormone imbalances that can lead to negative conditions such as PMS, PCOS, endometriosis, fibroid tumors, menopausal symptoms, weight problems and the list goes on. Recent research is positive so far that DIM improves weight loss resistance due to hormonal imbalance.
Due to its crystalline structure, absorption of DIM when given orally simply as a powder in a capsule is minimal, similar to CoQ10. DIM absorption can be greatly enhanced by emulsifying it with lecithin in rice bran oil, including with it compounds that hold it in solution such as beeswax, and finally adding fat-soluble nutrients that aid absorption through the gut wall. DIM-Avail is a unique combination of such ingredients. DIM-Avail uses proven technology recently shown in human subjects to have far superior bioavailability and peak absorption rates.
Product Contains: Diindolylmethane (DIM) 100 mg
Other Ingredients: Rice bran oil, gelatin, lecithin, glycerin, beeswax, mixed tocopherols (vitamin E), d.salina, turmeric and annatto (as colorants).
This product does not contain: wheat, yeast, gluten, eggs, dairy, corn, artificial colors, flavors, sugars, or preservatives
Serving Size: 1 softgel
Recommended Use: As a dietary supplement, take one softgel per day or as directed by your health care practitioner.